pentobarbital will lower the extent or effect of etonogestrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will reduce the level or impact of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Potent CYP3A4 inducers are anticipated to cause considerable decreases in sildenafil plasma amounts
pentobarbital will lessen the extent or result of finasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Mysterious.
pentobarbital will lower the extent or effect of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic result of elbasvir/grazoprevir may be minimized if coadministered with robust CYP3A inducers and is consequently contraindicated.
pentobarbital will decrease the extent or influence of dienogest/estradiol valerate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Women of all ages must not pick estradiol valerate/dienogest as their contraceptive even though using robust CYP3A4 inducers on account of possible lower in contraceptive efficacy.
pentobarbital will reduce the level or influence of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. The efficacy of hormonal contraceptives could possibly be lessened. Utilization of a nonhormonal contraceptive is usually recommended.
pentobarbital will lessen the extent or effect of carbamazepine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will reduce the extent or influence of etravirine by impacting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Keep an eye on.
Contraindicated (1)pentobarbital will lower the level or influence of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers may lead to lowered serum concentrations and loss of antimalarial efficacy
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pentobarbital will reduce the level or impact of buprenorphine buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will minimize the extent or influence of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to the minimize in fentanyl plasma concentrations, insufficient efficacy or, probably, development of a withdrawal syndrome in a affected person that has produced Actual physical dependence to fentanyl.
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pentobarbital will lower the extent or impact of propafenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.